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HTR-PMMA Patient-Matched Implant

Biomet Healthcare Professionals Microfixation HTR-PMMA Patient-Matched Implant

HTR-PMMA is a technology-driven, cranial patient-matched implant designed to achieve cosmesis of the skull resulting from tumor, trauma, or deformity.

The unique process of developing an HTR-PMMA implant converts patient CT-Scan data into 3-D images. These images are used to create anatomical models, which are then used to build the patient-matched implants.

HTR-PMMA is designed to provide:

  • Four fit options
  • Implant pre-plating
  • Simplified CT data Transfer through FTP and PACs
  • A porous implant that permits fibrovasacular ingrowth and potential for bony attachment1
  • Hydrophilic properties which allow for pre-operative antibiotic solution bath1


  • Patient Specific Anatomic Fit
  • HTR-PMMA is designed and manufactured based on uncompressed DICOM CT data.
  • Hydrophilic
  • Allows for placement of implant into antibiotic solution pre-operatively; enables vascular flow post-operatively.2
  • Porous
  • Pore diameter ranges from 150 - 350 microns supports possible connective tissue and bone ingrowth.1
  • Rigid and Strong
  • Implants have a rigidity similar to bone, with a compressive strength of 5,000 psi.1
  • Negative Surface Charge
  • May have minor positive effects on bony ingrowth and inhibition of bacterial adhesion.1
  • Radiopaque
  • Implants can be conveniently and accurately monitored post-operatively.3


HTR-PMMA (Hard Tissue Replacement) polymer implants are intended for reconstruction and augmentation in craniofacial procedures. They are intended to fill voids or defects in bone resulting from disease, traumatic injury or surgical trauma. These devices can be used in aesthetic reconstructive procedures where augmentation or change in bony contours is desired.

  1. Eppley, Barry L., Matthew Kilgo, and John J. Coleman. Cranial Reconstruction with Computer Generated Hard Tissue Replacement Patient-Matched Implants: Indications, Surgical Technique, and Long Term Follow Up. Plastic and Reconstructive Surgery (2001):109.3: 864-71. p. 869
  2. Eppley, Barry L., Michael Sadove, Hans Holmstrom, and Karl-Erik Kahnberg. HTR Polymer Facial Implants: A Five Year Clinical Experience. Aesthetic Plastic Surgery (1995): 445-50
  3. Kwan, JY, et al. Clinical and Histological Evaluations of Hard tissue Replacement Alloplastic Grafting Material, Case Reports. Abstract 89 46 02; Compendium of Dental Residents’ Research Projects and Literature Reviews, USAF School of Aerospace