Plasmax™: Oral - Tooth Extraction
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Leuthold B, Bormann R. Autologous fibrin glue – a local hemostatic agent following dental surgical interventions in patients undergoing anticoagulant therapy. Zahn Mund Kieferheilkd Zentralbl 1989;77(3):268-72.
Summary: Autologous fibrin glue was used to stop bleeding after tooth extraction in 39 patients treated with anticoagulants. A total of 69 teeth were extracted, 64 of which experienced no additional bleeding. In all of the 5 patients who experienced secondary bleeding, a second application of fibrin glue achieved hemostasis.
Quotation: “Autologous fibrin adhesives…prepared from the blood of the patient who is on anticoagulant therapy, is very suitable as local hemostatic after stomatologicalsurgical interventions.”
Rakocz M, Lavie G, Martinowitz U. Glanzmann’s thrombasthenia: the use of autologous fibrin glue in tooth extractions. ASDC J Dent Child 1995;62(2):129-31.
Abstract: “Three teeth were extracted in three sessions in a 15-year-old girl with Glanzmann's thrombasthenia who suffered in the past severe bleeding and required platelet transfusions. The extraction sites were treated locally with autologous fibrin glue in adjunct of tranexamic acid swish and swallow rinses. No systemic platelet infusion was employed as a preventive measure. No postoperative bleeding occurred.”
Carter G, Goss AN, Lloyd J, Tocchetti R. Local haemostasis with autologous fibrin glue following surgical enucleation of a large cystic lesion in a therapeutically anticoagulated patient. Br J Oral Maxillofac Surg 2003;41(1):275-276.
Summary: Autologous fibrin glue was used to achieve local hemostasis after the surgical removal of an unerupted premolar and enucleation of the associated dentigerous cyst in a patient using Warfarin. The patient had no postoperative complications or bleeding. At follow-up four years later, complete bony infill had occurred.
Quotation: “Our case report shows the effectiveness of autologous fibrin glue in controlling haemostasis in an operation associated with a higher risk of bleeding risk than a simple dental extraction.”