Plasmax™: Oral - Mandible
Some of the information contained on this webpage pertains to products, indications for use of products and/or therapies that are only available outside the United States and have not been approved or cleared for marketing by the United States Food & Drug Administration.
Tayapongsak P, O’Brien DA, Monteiro CB, Arceo-Diaz LY. Autologous Fibrin Adhesive in Mandibular Reconstruction with Particulate Cancellous Bone and Marrow. J Oral Maxillofac Surg 1994;52:161-5.
Summary: Autologous fibrin adhesive was used with particulate cancellous bone and marrow in mandibular reconstruction surgery in 33 cases. The bone remodeling process occurred about 50% faster than in previous cases where fibrin adhesive was not used.
Quotation: “In addition to adhesive and hemostatic properties, it helped the remodeling process begin about 50% earlier by providing the substratum for migration of mesenchymal cells, accelerating revascularization and migration of fibroblasts, stimulating the growth of both fibroblasts and osteoblasts, and slowing the multiplication of microorganisms.”
“The histologic findings demonstrated that AFA [autologous fibrin adhesive] is a very porous mass that allows nutrients and oxygen to reach the bone cells freely, thus enabling them to undergo the proliferation and osteoid production associated with phase I bone formation.”
Tayapongsak P, Pijut LJ, Scheffer RB. Inferior border titanium cribs in mandibular reconstruction. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995;79(1):10-17.
Summary: Fourteen patients underwent mandibular reconstruction with autogenous particulate cancellous and bone marrow, autologous fibrin adhesive, and custom-made inferior border titanium cribs, with positive results.
Quotation: “Autologous fibrin adhesive held the bone particles firmly together and accelerated the bone graft healing, which enabled the early removal of the intermaxillary fixation and restoration of the masticatory function.”